PHF6 Antibody - N-terminal region

Catalog Number: ASB-ARP51237_T100
Article Name: PHF6 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP51237_T100
Supplier Catalog Number: ARP51237_T100
Alternative Catalog Number: ASB-ARP51237_T100-25UL,ASB-ARP51237_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF6
Alternative Names: BFLS, BORJ, CENP-31
PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears.This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 41kDa
NCBI: 84295
UniProt: Q8IWS0
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-PHF6 Antibody Titration: 5.0ug/ml
Positive Control: Jurkat cell lysate
Sample Type: HEK293T cells transfected with a plasmid for over expression of myc-tagged PHF6Primary Dilution: 1:1000Secondary (goat anti-rabbit HRP) Dilution: 1:1000
PHF6 antibody - N-terminal region (ARP51237_T100) in Human Jurkat using Western Blot