CYP1B1 Antibody - middle region

Catalog Number: ASB-ARP51761_P050
Article Name: CYP1B1 Antibody - middle region
Biozol Catalog Number: ASB-ARP51761_P050
Supplier Catalog Number: ARP51761_P050
Alternative Catalog Number: ASB-ARP51761_P050-25UL,ASB-ARP51761_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP1B1
Alternative Names: CP1B, ASGD6, GLC3A, CYPIB1, P4501B1
CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 61kDa
NCBI: 1545
UniProt: Q16678
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-CYP1B1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Liver
Lanes:
Lane 1: Human lung microsome lysate
Lane 2-5: 150 ug mouse lung microsome lysate
Primary Antibody Dilution:
1: 1000
Secondary Antibody:
Anti-rabbit HRP
Secondary Antibody Dilution:
1: 10000
Gene Name:
CYP1B1
Submitted by:
Jing Peng, Fox Chase Cancer Center
CYP1B1 antibody - middle region (ARP51761_P050) in Human Liver using Western Blot