CENPB Antibody - C-terminal region
Catalog Number:
ASB-ARP51969_P050
- Images (3)
| Article Name: | CENPB Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP51969_P050 |
| Supplier Catalog Number: | ARP51969_P050 |
| Alternative Catalog Number: | ASB-ARP51969_P050-25UL,ASB-ARP51969_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Equine, Human, Mouse, Porcine, Rat, Sheep, Yeast, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human CENPB |
| CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-CENPB Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:500 Positive Control: Jurkat cell lysate |
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Host: Rabbit Target Name: CENPB Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 0.5ug/ml |
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CENPB antibody - C-terminal region (ARP51969_P050) in Human Jurkat using Western Blot |
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