Cish Antibody - N-terminal region

Catalog Number: ASB-ARP52798_P050
Article Name: Cish Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP52798_P050
Supplier Catalog Number: ARP52798_P050
Alternative Catalog Number: ASB-ARP52798_P050-25UL,ASB-ARP52798_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse
Alternative Names: C, CI, Cis, F17, F23, CIS1, SOCS, CIS-1
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 28kDa
NCBI: 12700
UniProt: Q62225
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-Cish Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Mouse Heart
Host: Rabbit
Target Name: CISH
Sample Tissue: Mouse Mouse Kidney
Antibody Dilution: 1ug/ml
Cish antibody - N-terminal region (ARP52798_P050) in Mouse Heart using Western Blot