SGMS2 Antibody - N-terminal region
Catalog Number:
ASB-ARP53078_P050
- Images (3)
| Article Name: | SGMS2 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP53078_P050 |
| Supplier Catalog Number: | ARP53078_P050 |
| Alternative Catalog Number: | ASB-ARP53078_P050-25UL,ASB-ARP53078_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human SGMS2 |
| Alternative Names: | CDL, SMS2 |
| SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).[supplied by OMIM]. Sequence Note: removed 3 bases from the 5 end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2142 BC041369.2 4-2145 |
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WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 293T cell lysate |
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Host: Rabbit Target: SGMS2 Positive control (+): Human Kidney (KI) Negative control (-): Human Placenta (PL) Antibody concentration: 1ug/ml |
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SGMS2 antibody - N-terminal region (ARP53078_P050) in Human 293T using Western Blot |
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