PDE12 Antibody - middle region
Catalog Number:
ASB-ARP53350_P050
- Images (3)
| Article Name: | PDE12 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP53350_P050 |
| Supplier Catalog Number: | ARP53350_P050 |
| Alternative Catalog Number: | ASB-ARP53350_P050-25UL,ASB-ARP53350_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human 2-PDE |
| Alternative Names: | 2-PDE, 2-PDE |
| 2-PDE is an enzyme that cleaves 2,5-phosphodiester bond linking adenosines of the 5-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. 2-PDE also cleaves 3,5-phosphodiester bond of oligoadenylates. 2-PDE play a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system. |
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WB Suggested Anti-PDE12 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: OVCAR-3 cell lysatePDE12 is supported by BioGPS gene expression data to be expressed in OVCAR3 |
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Host: Rabbit Target Name: PDE12 Sample Tissue: Human Jurkat Antibody Dilution: 1.0ug/ml |
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PDE12 antibody - middle region (ARP53350_P050) in Human Jurkat using Western Blot |
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