FGFR1OP Antibody - middle region

Catalog Number: ASB-ARP53670_P050
Article Name: FGFR1OP Antibody - middle region
Biozol Catalog Number: ASB-ARP53670_P050
Supplier Catalog Number: ARP53670_P050
Alternative Catalog Number: ASB-ARP53670_P050-25UL,ASB-ARP53670_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGFR1OP
Alternative Names: FOP, FGFR1OP
FGFR1OP is a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 42kDa
NCBI: 11116
UniProt: O95684
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-FGFR1OP Antibody
Catalog Number: ARP53670_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-FGFR1OP Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Liver
FGFR1OP antibody - middle region (ARP53670_P050) in Human Liver using Western Blot