GTPBP4 Antibody - C-terminal region
Catalog Number:
ASB-ARP54884_P050
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| Article Name: | GTPBP4 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP54884_P050 |
| Supplier Catalog Number: | ARP54884_P050 |
| Alternative Catalog Number: | ASB-ARP54884_P050-25UL,ASB-ARP54884_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human GTPBP4 |
| Alternative Names: | NGB, CRFG, NOG1 |
| GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. Active in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. Active in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. |
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WB Suggested Anti-GTPBP4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: MCF7 cell lysateGTPBP4 is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells |
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GTPBP4 antibody - C-terminal region (ARP54884_P050) in Human MCF7 using Western Blot |
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