Chmp2b Antibody - N-terminal region
Catalog Number:
ASB-ARP54967_P050
- Images (2)
| Article Name: | Chmp2b Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP54967_P050 |
| Supplier Catalog Number: | ARP54967_P050 |
| Alternative Catalog Number: | ASB-ARP54967_P050-25UL,ASB-ARP54967_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Chmp2b |
| Alternative Names: | RGD1306781 |
| Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis . |
| Clonality: | Polyclonal |
| Concentration: | 0.5 mg/ml |
| Molecular Weight: | 23kDa |
| NCBI: | 363720 |
| Form: | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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WB Suggested Anti-Chmp2b Antibody Titration: 1.0 ug/ml Positive Control: Rat Spleen |
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Chmp2b Antibody - N-terminal region (ARP54967_P050) in Rat Spleen using Western Blot |
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