Bovine, Canine, Equine, Guinea pig, Human, Rabbit, Rat, Yeast
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human PMS2
Alternative Names:
MLH4, PMSL2, HNPCC4, MMRCS4, PMS2CL
PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-PMS2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysatePMS2 is supported by BioGPS gene expression data to be expressed in HepG2
Sample Type: HeLa extractDilution: 1:1000
PMS2 antibody - middle region (ARP56117_P050) in Human HepG2 using Western Blot
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