GLRX2 Antibody - middle region
Catalog Number:
ASB-ARP57792_P050
- Images (3)
| Article Name: | GLRX2 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP57792_P050 |
| Supplier Catalog Number: | ARP57792_P050 |
| Alternative Catalog Number: | ASB-ARP57792_P050-25UL,ASB-ARP57792_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human GLRX2 |
| Alternative Names: | GRX2, CGI-133 |
| GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression of GLRX2 decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release. |
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WB Suggested Anti-GLRX2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human heart |
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Host: Rabbit Target Name: GLRX2 Sample Tissue: Human A549 Whole Cell Antibody Dilution: 1ug/ml |
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GLRX2 antibody - middle region (ARP57792_P050) in Human Heart using Western Blot |
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