RUNX1T1 Antibody - middle region
Catalog Number:
ASB-ARP58127_P050
- Images (3)
| Article Name: | RUNX1T1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP58127_P050 |
| Supplier Catalog Number: | ARP58127_P050 |
| Alternative Catalog Number: | ASB-ARP58127_P050-25UL,ASB-ARP58127_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human RUNX1T1 |
| Alternative Names: | CDR, ETO, MTG8, AML1T1, ZMYND2, CBFA2T1, AML1-MTG8 |
| RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5-region of the RUNX1 gene fused to the 3-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5-region of the RUNX1 gene fused to the 3-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene. |
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RUNX1T1 antibody - middle region (ARP58127_P050) Catalog Number: ARP58127_P050 Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Nucleus in hepatocytes Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-RUNX1T1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 293T cell lysate |
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RUNX1T1 antibody - middle region (ARP58127_P050) in Human 293T using Western Blot |
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