PPP1CA Antibody - N-terminal region

Catalog Number: ASB-ARP58652_P050
Article Name: PPP1CA Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP58652_P050
Supplier Catalog Number: ARP58652_P050
Alternative Catalog Number: ASB-ARP58652_P050-25UL,ASB-ARP58652_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP1CA
Alternative Names: PP1A, PP-1A, PPP1A, PP1alpha
PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 38kDa
NCBI: 5499
UniProt: Q07161
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-PPP1CA Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysatePPP1CA is supported by BioGPS gene expression data to be expressed in Jurkat
WB Suggested Anti-PPP1CA Antibody
Positive Control: Lane 1: 40ug HEK293 lysate Lane 2: 40ug H1299 lysate
Primary Antibody Dilution : 1:1000
Secondary Antibody : Goat anti-rabbit-HRP
Secondry Antibody Dilution : 1:5000
Submitted by: Jose Luis Rosa, Universitat de Barcelona
PPP1CA antibody - N-terminal region (ARP58652_P050) in Human Jurkat using Western Blot