The immunogen is a synthetic peptide directed towards the N terminal region of human CASP7
Alternative Names:
MCH3, CMH-1, LICE2, CASP-7, ICE-LAP3
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-CASP7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: OVCAR-3 cell lysateCASP7 is supported by BioGPS gene expression data to be expressed in OVCAR3