CD3E Antibody - middle region
Catalog Number:
ASB-ARP59097_P050
- Images (3)
| Article Name: | CD3E Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP59097_P050 |
| Supplier Catalog Number: | ARP59097_P050 |
| Alternative Catalog Number: | ASB-ARP59097_P050-25UL,ASB-ARP59097_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human CD3E |
| Alternative Names: | T3E, TCRE, IMD18 |
| The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |



