COL1A1 Antibody - C-terminal region

Catalog Number: ASB-ARP59998_P050
Article Name: COL1A1 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP59998_P050
Supplier Catalog Number: ARP59998_P050
Alternative Catalog Number: ASB-ARP59998_P050-25UL,ASB-ARP59998_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human COL1A1
Alternative Names: OI1, OI2, OI3, OI4, EDSC, CAFYD, EDSARTH1
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 137kDa
NCBI: 1277
UniProt: P02452
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-COL1A1 Antibody
Catalog Number: ARP59998_P050
Formalin Fixed Paraffin Embedded Tissue: Human Urinary Bladder Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-COL1A1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain
COL1A1 antibody - C-terminal region (ARP59998_P050) in Human Brain using Western Blot