BRCC3 Antibody - C-terminal region

Catalog Number: ASB-ARP61990_P050
Article Name: BRCC3 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP61990_P050
Supplier Catalog Number: ARP61990_P050
Alternative Catalog Number: ASB-ARP61990_P050-25UL,ASB-ARP61990_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IF, WB
Species Reactivity: Bovine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Alternative Names: C6.1A, BRCC36, CXorf53
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 35kDa
NCBI: 79184
UniProt: P46736
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type:
MCF7
Primary Antibody Dilution:
4 ug/ml
Secondary Antibody:
Anti-rabbit Alexa 546
Secondary Antibody Dilution:
2 ug/ml
Gene Name:
BRCC3
WB Suggested Anti-BRCC3 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Heart
Host: Rabbit
Target Name: BRCC3
Sample Type: Human Hela
Antibody Dilution: 1.0ug/mlBRCC3 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
BRCC3 antibody - C-terminal region (ARP61990_P050) in Human Fetal heart using Western Blot