RAF1 Antibody - middle region
Catalog Number:
ASB-ARP72539_P050
- Images (3)
| Article Name: | RAF1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP72539_P050 |
| Supplier Catalog Number: | ARP72539_P050 |
| Alternative Catalog Number: | ASB-ARP72539_P050-25UL,ASB-ARP72539_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of Human RAF1 |
| Alternative Names: | NS5, CRAF, Raf-1, c-Raf, CMD1NN |
| This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. |
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Host: Rabbit Target Name: RAF1 Sample Type: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml |
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Host: Mouse Target Name: RAF1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml |
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RAF1 Antibody - middle region (ARP72539_P050) in Human Jurkat using Western Blot |
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