LMNA Antibody - C-terminal region

Catalog Number: ASB-ARP74976_P050
Article Name: LMNA Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP74976_P050
Supplier Catalog Number: ARP74976_P050
Alternative Catalog Number: ASB-ARP74976_P050-25UL,ASB-ARP74976_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Human
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LMNA
Alternative Names: FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, MADA, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1, LGMD1B
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 73kDa
NCBI: 4000
UniProt: P02545
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-LMNA Antibody
Catalog Number: ARP74976_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue
Observed Staining: Nucleus
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Host: Rabbit
Target Name: LMNA
Sample Type: ACHN Whole Cell lysates
Antibody Dilution: 1.0ug/ml
LMNA Antibody (ARP74976_P050) in Human ACHN Whole Cell using Western Blot