SHC1 Antibody - middle region
Catalog Number:
ASB-ARP76586_P050
- Images (3)
| Article Name: | SHC1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP76586_P050 |
| Supplier Catalog Number: | ARP76586_P050 |
| Alternative Catalog Number: | ASB-ARP76586_P050-25UL,ASB-ARP76586_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human SHC1 |
| Alternative Names: | SHC, SHCA |
| This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. |
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Host: Rabbit Target Name: SHC1 Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 1.0ug/ml |
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Host: Mouse Target Name: SHC1 Sample Tissue: Mouse Spleen Antibody Dilution: 1ug/ml |
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SHC1 Antibody - middle region (ARP76586_P050) in Human Jurkat Whole Cell using Western Blot |
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