DIO2 Antibody - middle region
Catalog Number:
ASB-ARP78117_P050
- Images (3)
| Article Name: | DIO2 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP78117_P050 |
| Supplier Catalog Number: | ARP78117_P050 |
| Alternative Catalog Number: | ASB-ARP78117_P050-25UL,ASB-ARP78117_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human DIO2 |
| Alternative Names: | D2, 5DII, SelY, DIOII, TXDI2, SELENOY |
| The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3,5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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Host: Rabbit Target Name: DIO2 Sample Tissue: ACHN Whole Cell lysates Antibody Dilution: 1ug/ml |
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Host: Rat Target Name: DIO2 Sample Tissue: Rat Skeletal Muscle Antibody Dilution: 1ug/ml |
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DIO2 Antibody - middle region (ARP78117_P050) in Human ACHN Whole Cell using Western Blot |
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