TYROBP Antibody - middle region
Catalog Number:
ASB-ARP79099_P050
- Images (3)
| Article Name: | TYROBP Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP79099_P050 |
| Supplier Catalog Number: | ARP79099_P050 |
| Alternative Catalog Number: | ASB-ARP79099_P050-25UL,ASB-ARP79099_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human TYROBP |
| Alternative Names: | DAP12, KARAP, PLOSL, PLOSL1 |
| This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. |
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Host: Rabbit Target Name: TYROBP Sample Tissue: Human HepG2 Whole Cell lysates Antibody Dilution: 1ug/ml |
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Host: Mouse Target Name: TYROBP Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml |
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TYROBP Antibody - middle region (ARP79099_P050) in Human HepG2 Whole Cell using Western Blot |
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