MDM2 Antibody - middle region

Catalog Number: ASB-ARP88009_P050
Article Name: MDM2 Antibody - middle region
Biozol Catalog Number: ASB-ARP88009_P050
Supplier Catalog Number: ARP88009_P050
Alternative Catalog Number: ASB-ARP88009_P050-25UL,ASB-ARP88009_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Human
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MDM2
Alternative Names: HDMX, LSKB, hdm2, ACTFS
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 55 kDa
NCBI: 4193
UniProt: Q00987-8
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: MDM2
Sample Tissue: Human Jurkat Whole Cell lysates
Antibody Dilution: 1ug/ml
ARP88009_P050
MDM2 Antibody - middle region (ARP88009_P050) in Human Jurkat Whole Cell using Western Blot