CDC42 Antibody - N-terminal region
Catalog Number:
ASB-AVARP01017_P050
- Images (4)
| Article Name: | CDC42 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-AVARP01017_P050 |
| Supplier Catalog Number: | AVARP01017_P050 |
| Alternative Catalog Number: | ASB-AVARP01017_P050-25UL,ASB-AVARP01017_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Canine, Rabbit |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human CDC42 |
| Alternative Names: | TKS, G25K, CDC42Hs |
| CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. |
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Rabbit Anti-CDC42 Antibody Catalog Number: AVARP01017_P050 Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue Observed Staining: Cytoplasm in hepatocytes Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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Rabbit Anti-CDC42 Antibody Catalog Number: AVARP01017_P050 Formalin Fixed Paraffin Embedded Tissue: Human Bone Marrow Tissue Observed Staining: Cytoplasm, Plasma membrane Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-CDC42 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: 721_B cell lysateCDC42 is supported by BioGPS gene expression data to be expressed in 721_B |
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CDC42 antibody - N-terminal region (AVARP01017_P050) in Human 721_B using Western Blot |
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