TRADD Antibody - middle region
Catalog Number:
ASB-AVARP02012_P050
- Images (3)
| Article Name: | TRADD Antibody - middle region |
| Biozol Catalog Number: | ASB-AVARP02012_P050 |
| Supplier Catalog Number: | AVARP02012_P050 |
| Alternative Catalog Number: | ASB-AVARP02012_P050-25UL,ASB-AVARP02012_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Canine, Equine, Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human TRADD |
| Alternative Names: | Hs.89862 |
| TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-TRADD Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: DU145 cell lysateThere is BioGPS gene expression data showing that TRADD is expressed in DU145 |
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Lanes: Lane 1: 10ug Tradd-HA-Strep-stable expression 293TREXFlpIn cells-Doxycycline induced Lane 2: 10ug ITradd-HA-Strep-stable expression 293TREXFlpIn cells-non-induced Lane 3: 10ug siRNA scrambled-MDA-MB-231 cells Lane 4: siRNA Tradd-MDA-MB-231 cells Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:2000 Gene Name: TRADD Submitted by: Dr. Tencho Tenev, The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research There is BioGPS gene expression data showing that TRADD is expressed in HEK293T |
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TRADD antibody - middle region (AVARP02012_P050) in Human DU145 using Western Blot |
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