TIAL1 Antibody - C-terminal region
Catalog Number:
ASB-AVARP02048_T100
- Images (4)
| Article Name: | TIAL1 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-AVARP02048_T100 |
| Supplier Catalog Number: | AVARP02048_T100 |
| Alternative Catalog Number: | ASB-AVARP02048_T100-25UL,ASB-AVARP02048_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human TIAL1 |
| Alternative Names: | TCBP, TIAR |
| The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif. |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Protein may be acetylated or phosphorylated. |
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WB Suggested Anti-TIAL1 Antibody Titration: 1.25ug/ml Positive Control: Jurkat cell lysateTIAL1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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Host: Rabbit Target: TIAL1 Positive control (+): Mouse Spleen (M-SP) Negative control (-): Mouse Liver (M-LI) Antibody concentration: 2ug/ml |
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TIAL1 antibody - C-terminal region (AVARP02048_T100) in Human Jurkat using Western Blot |
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