TNFRSF18 Antibody - C-terminal region
Catalog Number:
ASB-AVARP02052_T100
- Images (3)
| Article Name: | TNFRSF18 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-AVARP02052_T100 |
| Supplier Catalog Number: | AVARP02052_T100 |
| Alternative Catalog Number: | ASB-AVARP02052_T100-25UL,ASB-AVARP02052_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18 |
| Alternative Names: | AITR, GITR, CD357, GITR-D, ENERGEN |
| The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |



