CCNT1 Antibody - N-terminal region
Catalog Number:
ASB-AVARP03021_P050
- Images (4)
| Article Name: | CCNT1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-AVARP03021_P050 |
| Supplier Catalog Number: | AVARP03021_P050 |
| Alternative Catalog Number: | ASB-AVARP03021_P050-25UL,ASB-AVARP03021_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human CCNT1 |
| Alternative Names: | CCNT, CYCT1, HIVE1 |
| CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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WB Suggested Anti-CCNT1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysateCCNT1 is supported by BioGPS gene expression data to be expressed in 721_B |
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Host: Rabbit Target Name: CCNT1 Sample Type: MCF7 Antibody Dilution: 1.0ug/mlCCNT1 is supported by BioGPS gene expression data to be expressed in MCF7 |
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Host: Rabbit Target Name: CCNT1 Sample Type: Hela Antibody Dilution: 1.0ug/mlCCNT1 is supported by BioGPS gene expression data to be expressed in HeLa |
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CCNT1 antibody - N-terminal region (AVARP03021_P050) in Human 721_B using Western Blot |
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