CDKN2B Antibody - middle region

Catalog Number: ASB-AVARP03047_P050
Article Name: CDKN2B Antibody - middle region
Biozol Catalog Number: ASB-AVARP03047_P050
Supplier Catalog Number: AVARP03047_P050
Alternative Catalog Number: ASB-AVARP03047_P050-25UL,ASB-AVARP03047_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Canine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDKN2B
Alternative Names: P15, MTS2, TP15, CDK4I, INK4B, p15INK4b
CDKN2Bs gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 15kDa
NCBI: 1030
UniProt: P42772
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-CDKN2B Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
Host: Rabbit
Target Name: CDKN2B
Sample Tissue: Human Lung Tumor
Antibody Dilution: 1ug/ml
CDKN2B antibody - middle region (AVARP03047_P050) in Human Jurkat using Western Blot