TOP2A Antibody - C-terminal region
Catalog Number:
ASB-AVARP04007_T100
- Images (3)
| Article Name: | TOP2A Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-AVARP04007_T100 |
| Supplier Catalog Number: | AVARP04007_T100 |
| Alternative Catalog Number: | ASB-AVARP04007_T100-25UL,ASB-AVARP04007_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human TOP2A |
| Alternative Names: | TOP2, TP2A, TOPIIA, TOP2alpha |
| TOP2A is a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. |
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Rabbit Anti-TOP2A antibody Catalog Number: AVARP04007 Paraffin Embedded Tissue: Human Liver cell Cellular Data: hepatocyte of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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WB Suggested Anti-TOP2A Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysateTOP2A is supported by BioGPS gene expression data to be expressed in HepG2 |
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TOP2A antibody - C-terminal region (AVARP04007_T100) in Human HepG2 using Western Blot |
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