CAV1 Antibody - N-terminal region

Catalog Number: ASB-AVARP09019_T100
Article Name: CAV1 Antibody - N-terminal region
Biozol Catalog Number: ASB-AVARP09019_T100
Supplier Catalog Number: AVARP09019_T100
Alternative Catalog Number: ASB-AVARP09019_T100-25UL,ASB-AVARP09019_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAV1
Alternative Names: CGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085
The scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 20kDa
NCBI: 857
UniProt: Q03135
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-CAV1 Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysate
CAV1 antibody - N-terminal region (AVARP09019_T100) in Human Jurkat using Western Blot