NAPA Antibody - N-terminal region
Catalog Number:
ASB-AVARP13049_T100
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| Article Name: | NAPA Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-AVARP13049_T100 |
| Supplier Catalog Number: | AVARP13049_T100 |
| Alternative Catalog Number: | ASB-AVARP13049_T100-25UL,ASB-AVARP13049_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Mouse, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human NAPA |
| Alternative Names: | SNAPA |
| The SNARE hypothesis is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. |
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