The antiserum was produced against synthesized peptide derived from human Annexin II.
Alternative Names:
annexin A2,annexin II,annexin-2,ANX2,ANX2L4,CAL1H,calpactin I heavy chain,calpactin I heavy polypeptide,calpactin-1 heavy chain,chromobindin 8,Chromobindin-8,epididymis secretory protein Li 270,epididymis secretory sperm binding protein,HEL-S-270,LIP2,lipocortin II,LPC2,LPC2D,P36,PAP-IV,placental anticoagulant protein IV,protein I.
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).
