OAT1 Antibody
Catalog Number:
ASB-OAAF05885
- Images (2)
| Article Name: | OAT1 Antibody |
| Biozol Catalog Number: | ASB-OAAF05885 |
| Supplier Catalog Number: | OAAF05885 |
| Alternative Catalog Number: | ASB-OAAF05885-100UG |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IF, IHC, IHC-P, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human OAT1. |
| Alternative Names: | HOAT1,hPAHT,hROAT1,OAT1,organic anion transporter 1,PAH transporter,PAHT,para-aminohippurate transporter,renal organic anion transporter 1,ROAT1,solute carrier family 22 (organic anion transporter), member 6,solute carrier family 22 member 6. |
| Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3-azido-3-deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate. |
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Immunohistochemistry analyzes of OAT1 antibody in paraffin-embedded human brain tissue. |
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Western blot analyzes of OAT1 antibody in extracts from mouse liver cells. |
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