The antiserum was produced against synthesized peptide derived from human SSB around the phosphorylation site of Ser366.
Alternative Names:
autoantigen La,La,la autoantigen,La ribonucleoprotein,La ribonucleoprotein domain family, member 3,La/SSB,LARP3,lupus La antigen,lupus La protein,sjoegren syndrome type B antigen,Sjogren syndrome antigen B,SS-B,SS-B/La protein.
Binds to the 3 poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597).
