A synthetic peptide corresponding to N-term of human 14.3.3 beta protein.
Alternative Names:
14-3-3 alpha,14-3-3 protein beta/alpha,epididymis secretory protein Li 1,GW128,HEL-S-1,HS1,KCIP-1,protein 1054,protein kinase C inhibitor protein-1,tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide,tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide,YWHAA.
The 14-3-3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein. 14.3.3 beta is highly expressed in brain tissue. It is critical to cell transformation and mitotic signaling.
