A synthetic peptide corresponding to the internal region of human FOXP2 protein. This sequence is identical to human, mouse, rat and dog
Alternative Names:
CAG repeat protein 44,CAGH44,forkhead box protein P2,forkhead/winged-helix transcription factor,SPCH1,TNRC10,trinucleotide repeat containing 10,trinucleotide repeat-containing gene 10 protein.
Forkhead/winged-helix box (Fox) genes are the transcriptional regulators and highly conserved across mammals. It contains a FOX DNA-binding domain and large polyglutamine tract. The FOXPs are involved in organogenesis and cell differentiation. FOXP2 gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. A mutation of FOXP2 was discovered in patients with severe defects in speech and language, such as speech disorder, autism.