NFYB (AAH05317, 1 a.a. ~ 207 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Alternative Names:
CAAT box DNA-binding protein subunit B,CBF-A,CBF-B,CCAAT-binding transcription factor subunit A,HAP3,NF-YB,nuclear transcription factor Y subunit B,nuclear transcription factor Y subunit beta,nuclear transcription factor Y, beta,Transcription factor NF-Y, B subunit.
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants. [provided by RefSeq
