NTRK3 (AAH13693, 41 a.a. ~ 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Alternative Names:
ETS related protein-neurotrophic receptor tyrosine kinase fusion protein,ETV6-NTRK3 fusion,gp145(trkC),GP145-TrkC,neurotrophic tyrosine kinase, receptor, type 3,NT-3 growth factor receptor,TRKC,tyrosine kinase receptor C.
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq
