PHF1 (NP_077084, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Alternative Names:
hPCl1,hPHF1,MTF2L2,PCL1,PHD finger protein 1,PHF2,polycomb-like 1,polycomb-like protein 1,TDRD19C,testicular tissue protein Li 140,tudor domain containing 19C.
This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
