Recombinant fusion protein containing a sequence corresponding to amino acids 190-280 of human PAX6 (NP_000271.1).
Conjugation:
Unconjugated
Alternative Names:
AN, AN1, AN2, FVH1, MGDA, WAGR, ASGD5, D11S812E
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peters anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
