NCK1 Antibody
Catalog Number:
ASB-OACA06623
- Images (3)
| Article Name: | NCK1 Antibody |
| Biozol Catalog Number: | ASB-OACA06623 |
| Supplier Catalog Number: | OACA06623 |
| Alternative Catalog Number: | ASB-OACA06623-100UL,ASB-OACA06623-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human, Rat |
| Immunogen: | Recombinant Human Cytoplasmic protein NCK1 protein (58-377AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | cytoplasmic protein NCK1,melanoma NCK protein,NCK,NCK adaptor protein 1,NCK tyrosine kinase,nck-1,NCKalpha,non-catalytic region of tyrosine kinase,SH2/SH3 adaptor protein NCK-alpha. |
| Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors. |
| Clonality: | Polyclonal |
| NCBI: | 4690 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human rectal cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human tonsil at dilution 1:100 |
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All lanes: Cytoplasmic protein NCK1 antibody at 4ug/ml+rat liver tissue Secondary Goat poly |
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