ILF3 Antibody
Catalog Number:
ASB-OACA06969
- Images (3)
| Article Name: | ILF3 Antibody |
| Biozol Catalog Number: | ASB-OACA06969 |
| Supplier Catalog Number: | OACA06969 |
| Alternative Catalog Number: | ASB-OACA06969-100UL,ASB-OACA06969-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Interleukin enhancer-binding factor 3 protein (785-894AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | CBTF,Double-stranded RNA-binding protein 76,double-stranded RNA-binding protein, 76 kD,DRBF,DRBP76,dsRNA binding protein NFAR-2/MPP4,interleukin enhancer binding factor 3, 90kD,interleukin enhancer binding factor 3, 90kDa,interleukin enhancer-binding factor 3,M phase phosphoprotein 4, nuclear factor associated with DS RNA,MMP4,M-phase phosphoprotein 4,MPHOSPH4,MPP4,MPP4110,NF110,NF110b,NF90,NF90a,NF90b,NF90c,NF90ctv,NFAR,NFAR-1,NFAR110,NFAR2,NFAR-2,NFAR90,NF-AT-90,nuclear factor associated with dsRNA,nuclear factor of activated T-cells 110 kDa,nuclear factor of activated T-cells 90 kDa,nuclear factor of activated T-cells, 90 kD,TCP110,TCP80,translational control protein 80. |
| RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back-splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons. Plays thereby a role in the back-splicing of a subset of circRNAs (PubMed:28625552). As a consequence, participates in a wide range of transcriptional and post-transcriptional processes. Upon viral infection, ILF3 accumulates in the cytoplasm and participates in the innate antiviral response (PubMed:21123651). Mechanistically, ILF3 becomes phosphorylated and activated by the double-stranded RNA-activated protein kinase/PKR which releases ILF3 from cellular mature circRNAs. In turn, unbound ILF3 molecules are able to interact with and thus inhibit viral mRNAs (PubMed:21123651, PubMed:28625552). |
| Clonality: | Polyclonal |
| NCBI: | 3609 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human cervical cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100 |
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All lanes: Interleukin enhancer-binding factor 3 antibody at 3ug/ml+HepG2 whole cell lysate Se |
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