TARDBP Antibody
Catalog Number:
ASB-OACA07038
- Images (3)
| Article Name: | TARDBP Antibody |
| Biozol Catalog Number: | ASB-OACA07038 |
| Supplier Catalog Number: | OACA07038 |
| Alternative Catalog Number: | ASB-OACA07038-100UL,ASB-OACA07038-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, IP, WB |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human TAR DNA-binding protein 43 protein (1-260AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | ALS10,TAR DNA-binding protein 43,TAR DNA-binding protein-43,TDP-43. |
| DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3 UTR. |
| Clonality: | Polyclonal |
| NCBI: | 23435 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human placenta at dilution 1:100 |
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All lanes: TAR DNA-binding protein 43 antibody at 8ug/ml Lane 1: Hela whole cell lysate L |
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