TDP1 Antibody
Catalog Number:
ASB-OACA07256
- Images (3)
| Article Name: | TDP1 Antibody |
| Biozol Catalog Number: | ASB-OACA07256 |
| Supplier Catalog Number: | OACA07256 |
| Alternative Catalog Number: | ASB-OACA07256-100UL,ASB-OACA07256-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, IP, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human Tyrosyl-DNA phosphodiesterase 1 protein (1-260AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | tyr-DNA phosphodiesterase 1,tyrosyl-DNA phosphodiesterase 1. |
| DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3-phosphodiester bond, giving rise to DNA with a free 3 phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3-phosphoglycolates on protruding 3 ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3exonuclease activity and can remove a single nucleoside from the 3end of DNA and RNA molecules with 3hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3phosphate. |
| Clonality: | Polyclonal |
| NCBI: | 55775 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human placenta at dilution 1:100 |
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All lanes: Tyrosyl-DNA phosphodiesterase 1 antibody at 8ug/ml Lane 1: MCF-7 whole cell lysate< |
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