DKK4 Antibody
Catalog Number:
ASB-OACA07346
- Images (3)
| Article Name: | DKK4 Antibody |
| Biozol Catalog Number: | ASB-OACA07346 |
| Supplier Catalog Number: | OACA07346 |
| Alternative Catalog Number: | ASB-OACA07346-100UL,ASB-OACA07346-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dickkopf-related protein 4 protein (19-224AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | dickkopf-4,dickkopf-related protein 4,DKK-4,hDkk-4. |
| Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). |
| Clonality: | Polyclonal |
| NCBI: | 27121 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human liver at dilution 1:100 |
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All lanes: Dickkopf-related protein 4 antibody at 8ug/ml Lane 1: jurkat whole cell lysate La |
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