DCP2 Antibody
Catalog Number:
ASB-OACA07411
- Images (3)
| Article Name: | DCP2 Antibody |
| Biozol Catalog Number: | ASB-OACA07411 |
| Supplier Catalog Number: | OACA07411 |
| Alternative Catalog Number: | ASB-OACA07411-100UL,ASB-OACA07411-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human m7GpppN-mRNA hydrolase protein (1-240AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | DCP2 decapping enzyme homolog,hDpc,m7GpppN-mRNA hydrolase,mRNA-decapping enzyme 2,Nucleoside diphosphate-linked moiety X motif 20,nudix (nucleoside diphosphate linked moiety X)-type motif 20,NUDT20. |
| Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs (PubMed:12417715, PubMed:12218187, PubMed:12923261, PubMed:21070968). Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5-phosphorylated mRNA fragment and 7m-GDP (PubMed:12486012, PubMed:12923261, PubMed:21070968). Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay (PubMed:14527413). Plays a role in replication-dependent histone mRNA degradation (PubMed:18172165). Has higher activity towards mRNAs that lack a poly(A) tail (PubMed:21070968). Has no activity towards a cap structure lacking an RNA moiety (PubMed:21070968). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573). |
| Clonality: | Polyclonal |
| NCBI: | 167227 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100 |
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All lanes: m7GpppN-mRNA hydrolase antibody at 7ug/ml Lane 1: Hela whole cell lysate Lane |
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