DUSP7 Antibody

Catalog Number: ASB-OACA07414
Article Name: DUSP7 Antibody
Biozol Catalog Number: ASB-OACA07414
Supplier Catalog Number: OACA07414
Alternative Catalog Number: ASB-OACA07414-100UL,ASB-OACA07414-50UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant Human Dual specificity protein phosphatase 7 protein (160-419AA)
Conjugation: Unconjugated
Alternative Names: dual specificity protein phosphatase 7,dual specificity protein phosphatase PYST2,MKPX,PYST2.
Dual specificity protein phosphatase (PubMed:9788880). Shows high activity towards MAPK1/ERK2 (PubMed:9788880). Also has lower activity towards MAPK14 and MAPK8 (PubMed:9788880). In arrested oocytes, plays a role in meiotic resumption (By similarity). Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB (By similarity). May also inactivate PRKCA and/or PRKCG (By similarity). Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly checkpoint (SAC) complex (By similarity).
Clonality: Polyclonal
NCBI: 1849
Form: Liquid
Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100
All lanes: Dual specificity protein phosphatase 7 antibody at 10ug/ml+HepG2 whole cell lysate
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