Recombinant Human Lymphokine-activated killer T-cell-originated protein kinase protein (1-322AA)
Conjugation:
Unconjugated
Alternative Names:
cancer/testis antigen 84,CT84,epididymis luminal protein 164,HEL164,lymphokine-activated killer T-cell-originated protein kinase,MAPKK-like protein kinase,Nori-3,PDZ-binding kinase,serine/threonine protein kinase,spermatogenesis-related protein kinase,SPK,T-LAK cell-originated protein kinase,TOPK.
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
