Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein (141-320AA)
Conjugation:
Unconjugated
Alternative Names:
aminoacyl tRNA synthase complex-interacting multifunctional protein 2,ARS-interacting multi-functional protein 2,HLD17,JTV1,JTV-1,multisynthase complex auxiliary component p38,multisynthetase complex auxiliary component p38,P38,protein JTV-1.
Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:19131329). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.